diff --git a/AUTHORS b/AUTHORS
index 4bb2cbb..cac58ca 100644
--- a/AUTHORS
+++ b/AUTHORS
@@ -135,7 +135,6 @@
 MIPS Technologies <*@mips.com>
 Mozilla Foundation <*@mozilla.com>
 Netgem S.A. <*@netgem.com>
-Nutanix Inc. <*@nutanix.com>
 NVIDIA Corporation <*@nvidia.com>
 Opera Software ASA <*@opera.com>
 Optical Tone Ltd <*@opticaltone.com>
diff --git a/api/video/BUILD.gn b/api/video/BUILD.gn
index 9fd2891..e6052fe 100644
--- a/api/video/BUILD.gn
+++ b/api/video/BUILD.gn
@@ -43,8 +43,6 @@
   sources = [
     "i420_buffer.cc",
     "i420_buffer.h",
-    "i444_buffer.cc",
-    "i444_buffer.h",
     "nv12_buffer.cc",
     "nv12_buffer.h",
     "video_codec_type.h",
diff --git a/api/video/DEPS b/api/video/DEPS
index 5a3e496..cf6770d 100644
--- a/api/video/DEPS
+++ b/api/video/DEPS
@@ -18,10 +18,6 @@
     "+rtc_base/memory/aligned_malloc.h",
   ],
 
-  "i444_buffer\.h": [
-    "+rtc_base/memory/aligned_malloc.h",
-  ],
-
   "nv12_buffer\.h": [
     "+rtc_base/memory/aligned_malloc.h",
   ],
diff --git a/api/video/i444_buffer.cc b/api/video/i444_buffer.cc
deleted file mode 100644
index 5f8b714..0000000
--- a/api/video/i444_buffer.cc
+++ /dev/null
@@ -1,211 +0,0 @@
-/*
- *  Copyright (c) 2021 The WebRTC project authors. All Rights Reserved.
- *
- *  Use of this source code is governed by a BSD-style license
- *  that can be found in the LICENSE file in the root of the source
- *  tree. An additional intellectual property rights grant can be found
- *  in the file PATENTS.  All contributing project authors may
- *  be found in the AUTHORS file in the root of the source tree.
- */
-#include "api/video/i444_buffer.h"
-
-#include <string.h>
-
-#include <algorithm>
-#include <utility>
-
-#include "api/video/i420_buffer.h"
-#include "rtc_base/checks.h"
-#include "rtc_base/ref_counted_object.h"
-#include "third_party/libyuv/include/libyuv/convert.h"
-#include "third_party/libyuv/include/libyuv/planar_functions.h"
-#include "third_party/libyuv/include/libyuv/scale.h"
-
-// Aligning pointer to 64 bytes for improved performance, e.g. use SIMD.
-static const int kBufferAlignment = 64;
-
-namespace webrtc {
-
-namespace {
-
-int I444DataSize(int height, int stride_y, int stride_u, int stride_v) {
-  return stride_y * height + stride_u * height + stride_v * height;
-}
-
-}  // namespace
-
-I444Buffer::I444Buffer(int width, int height)
-    : I444Buffer(width, height, width, (width), (width)) {}
-
-I444Buffer::I444Buffer(int width,
-                       int height,
-                       int stride_y,
-                       int stride_u,
-                       int stride_v)
-    : width_(width),
-      height_(height),
-      stride_y_(stride_y),
-      stride_u_(stride_u),
-      stride_v_(stride_v),
-      data_(static_cast<uint8_t*>(
-          AlignedMalloc(I444DataSize(height, stride_y, stride_u, stride_v),
-                        kBufferAlignment))) {
-  RTC_DCHECK_GT(width, 0);
-  RTC_DCHECK_GT(height, 0);
-  RTC_DCHECK_GE(stride_y, width);
-  RTC_DCHECK_GE(stride_u, (width));
-  RTC_DCHECK_GE(stride_v, (width));
-}
-
-I444Buffer::~I444Buffer() {}
-
-// static
-rtc::scoped_refptr<I444Buffer> I444Buffer::Create(int width, int height) {
-  return new rtc::RefCountedObject<I444Buffer>(width, height);
-}
-
-// static
-rtc::scoped_refptr<I444Buffer> I444Buffer::Create(int width,
-                                                  int height,
-                                                  int stride_y,
-                                                  int stride_u,
-                                                  int stride_v) {
-  return new rtc::RefCountedObject<I444Buffer>(width, height, stride_y,
-                                               stride_u, stride_v);
-}
-
-// static
-rtc::scoped_refptr<I444Buffer> I444Buffer::Copy(
-    const I444BufferInterface& source) {
-  return Copy(source.width(), source.height(), source.DataY(), source.StrideY(),
-              source.DataU(), source.StrideU(), source.DataV(),
-              source.StrideV());
-}
-
-// static
-rtc::scoped_refptr<I444Buffer> I444Buffer::Copy(int width,
-                                                int height,
-                                                const uint8_t* data_y,
-                                                int stride_y,
-                                                const uint8_t* data_u,
-                                                int stride_u,
-                                                const uint8_t* data_v,
-                                                int stride_v) {
-  // Note: May use different strides than the input data.
-  rtc::scoped_refptr<I444Buffer> buffer = Create(width, height);
-  RTC_CHECK_EQ(0, libyuv::I444Copy(data_y, stride_y, data_u, stride_u, data_v,
-                                   stride_v, buffer->MutableDataY(),
-                                   buffer->StrideY(), buffer->MutableDataU(),
-                                   buffer->StrideU(), buffer->MutableDataV(),
-                                   buffer->StrideV(), width, height));
-  return buffer;
-}
-
-// static
-rtc::scoped_refptr<I444Buffer> I444Buffer::Rotate(
-    const I444BufferInterface& src,
-    VideoRotation rotation) {
-  RTC_CHECK(src.DataY());
-  RTC_CHECK(src.DataU());
-  RTC_CHECK(src.DataV());
-
-  int rotated_width = src.width();
-  int rotated_height = src.height();
-  if (rotation == webrtc::kVideoRotation_90 ||
-      rotation == webrtc::kVideoRotation_270) {
-    std::swap(rotated_width, rotated_height);
-  }
-
-  rtc::scoped_refptr<webrtc::I444Buffer> buffer =
-      I444Buffer::Create(rotated_width, rotated_height);
-
-  RTC_CHECK_EQ(0,
-               libyuv::I444Rotate(
-                   src.DataY(), src.StrideY(), src.DataU(), src.StrideU(),
-                   src.DataV(), src.StrideV(), buffer->MutableDataY(),
-                   buffer->StrideY(), buffer->MutableDataU(), buffer->StrideU(),
-                   buffer->MutableDataV(), buffer->StrideV(), src.width(),
-                   src.height(), static_cast<libyuv::RotationMode>(rotation)));
-
-  return buffer;
-}
-
-rtc::scoped_refptr<I420BufferInterface> I444Buffer::ToI420() {
-  rtc::scoped_refptr<I420Buffer> i420_buffer =
-      I420Buffer::Create(width(), height());
-  libyuv::I444ToI420(DataY(), StrideY(), DataU(), StrideU(), DataV(), StrideV(),
-                     i420_buffer->MutableDataY(), i420_buffer->StrideY(),
-                     i420_buffer->MutableDataU(), i420_buffer->StrideU(),
-                     i420_buffer->MutableDataV(), i420_buffer->StrideV(),
-                     width(), height());
-  return i420_buffer;
-}
-
-void I444Buffer::InitializeData() {
-  memset(data_.get(), 0,
-         I444DataSize(height_, stride_y_, stride_u_, stride_v_));
-}
-
-int I444Buffer::width() const {
-  return width_;
-}
-
-int I444Buffer::height() const {
-  return height_;
-}
-
-const uint8_t* I444Buffer::DataY() const {
-  return data_.get();
-}
-const uint8_t* I444Buffer::DataU() const {
-  return data_.get() + stride_y_ * height_;
-}
-const uint8_t* I444Buffer::DataV() const {
-  return data_.get() + stride_y_ * height_ + stride_u_ * ((height_));
-}
-
-int I444Buffer::StrideY() const {
-  return stride_y_;
-}
-int I444Buffer::StrideU() const {
-  return stride_u_;
-}
-int I444Buffer::StrideV() const {
-  return stride_v_;
-}
-
-uint8_t* I444Buffer::MutableDataY() {
-  return const_cast<uint8_t*>(DataY());
-}
-uint8_t* I444Buffer::MutableDataU() {
-  return const_cast<uint8_t*>(DataU());
-}
-uint8_t* I444Buffer::MutableDataV() {
-  return const_cast<uint8_t*>(DataV());
-}
-
-void I444Buffer::CropAndScaleFrom(const I444BufferInterface& src,
-                                  int offset_x,
-                                  int offset_y,
-                                  int crop_width,
-                                  int crop_height) {
-  RTC_CHECK_LE(crop_width, src.width());
-  RTC_CHECK_LE(crop_height, src.height());
-  RTC_CHECK_LE(crop_width + offset_x, src.width());
-  RTC_CHECK_LE(crop_height + offset_y, src.height());
-  RTC_CHECK_GE(offset_x, 0);
-  RTC_CHECK_GE(offset_y, 0);
-
-  const uint8_t* y_plane = src.DataY() + src.StrideY() * offset_y + offset_x;
-  const uint8_t* u_plane = src.DataU() + src.StrideU() * offset_y + offset_x;
-  const uint8_t* v_plane = src.DataV() + src.StrideV() * offset_y + offset_x;
-  int res =
-      libyuv::I444Scale(y_plane, src.StrideY(), u_plane, src.StrideU(), v_plane,
-                        src.StrideV(), crop_width, crop_height, MutableDataY(),
-                        StrideY(), MutableDataU(), StrideU(), MutableDataV(),
-                        StrideV(), width(), height(), libyuv::kFilterBox);
-
-  RTC_DCHECK_EQ(res, 0);
-}
-
-}  // namespace webrtc
diff --git a/api/video/i444_buffer.h b/api/video/i444_buffer.h
deleted file mode 100644
index d46c245..0000000
--- a/api/video/i444_buffer.h
+++ /dev/null
@@ -1,104 +0,0 @@
-/*
- *  Copyright (c) 2021 The WebRTC project authors. All Rights Reserved.
- *
- *  Use of this source code is governed by a BSD-style license
- *  that can be found in the LICENSE file in the root of the source
- *  tree. An additional intellectual property rights grant can be found
- *  in the file PATENTS.  All contributing project authors may
- *  be found in the AUTHORS file in the root of the source tree.
- */
-
-#ifndef API_VIDEO_I444_BUFFER_H_
-#define API_VIDEO_I444_BUFFER_H_
-
-#include <stdint.h>
-
-#include <memory>
-
-#include "api/scoped_refptr.h"
-#include "api/video/video_frame_buffer.h"
-#include "api/video/video_rotation.h"
-#include "rtc_base/memory/aligned_malloc.h"
-#include "rtc_base/system/rtc_export.h"
-
-namespace webrtc {
-
-// Plain I444 buffer in standard memory.
-// I444 represents an image with in YUV format withouth any chroma subsampling.
-// https://en.wikipedia.org/wiki/Chroma_subsampling#4:4:4
-class RTC_EXPORT I444Buffer : public I444BufferInterface {
- public:
-  static rtc::scoped_refptr<I444Buffer> Create(int width, int height);
-  static rtc::scoped_refptr<I444Buffer> Create(int width,
-                                               int height,
-                                               int stride_y,
-                                               int stride_u,
-                                               int stride_v);
-
-  // Create a new buffer and copy the pixel data.
-  static rtc::scoped_refptr<I444Buffer> Copy(const I444BufferInterface& buffer);
-
-  static rtc::scoped_refptr<I444Buffer> Copy(int width,
-                                             int height,
-                                             const uint8_t* data_y,
-                                             int stride_y,
-                                             const uint8_t* data_u,
-                                             int stride_u,
-                                             const uint8_t* data_v,
-                                             int stride_v);
-
-  // Returns a rotated copy of |src|.
-  static rtc::scoped_refptr<I444Buffer> Rotate(const I444BufferInterface& src,
-                                               VideoRotation rotation);
-
-  rtc::scoped_refptr<I420BufferInterface> ToI420() final;
-  const I420BufferInterface* GetI420() const final { return nullptr; }
-
-  // Sets all three planes to all zeros. Used to work around for
-  // quirks in memory checkers
-  // (https://bugs.chromium.org/p/libyuv/issues/detail?id=377) and
-  // ffmpeg (http://crbug.com/390941).
-  // TODO(nisse): Deprecated. Should be deleted if/when those issues
-  // are resolved in a better way. Or in the mean time, use SetBlack.
-  void InitializeData();
-
-  int width() const override;
-  int height() const override;
-  const uint8_t* DataY() const override;
-  const uint8_t* DataU() const override;
-  const uint8_t* DataV() const override;
-
-  int StrideY() const override;
-  int StrideU() const override;
-  int StrideV() const override;
-
-  uint8_t* MutableDataY();
-  uint8_t* MutableDataU();
-  uint8_t* MutableDataV();
-
-  // Scale the cropped area of |src| to the size of |this| buffer, and
-  // write the result into |this|.
-  void CropAndScaleFrom(const I444BufferInterface& src,
-                        int offset_x,
-                        int offset_y,
-                        int crop_width,
-                        int crop_height);
-
- protected:
-  I444Buffer(int width, int height);
-  I444Buffer(int width, int height, int stride_y, int stride_u, int stride_v);
-
-  ~I444Buffer() override;
-
- private:
-  const int width_;
-  const int height_;
-  const int stride_y_;
-  const int stride_u_;
-  const int stride_v_;
-  const std::unique_ptr<uint8_t, AlignedFreeDeleter> data_;
-};
-
-}  // namespace webrtc
-
-#endif  // API_VIDEO_I444_BUFFER_H_
diff --git a/api/video/test/BUILD.gn b/api/video/test/BUILD.gn
index 5b0d57b..1573e78 100644
--- a/api/video/test/BUILD.gn
+++ b/api/video/test/BUILD.gn
@@ -12,7 +12,6 @@
   testonly = true
   sources = [
     "color_space_unittest.cc",
-    "i444_buffer_unittest.cc",
     "nv12_buffer_unittest.cc",
     "video_adaptation_counters_unittest.cc",
     "video_bitrate_allocation_unittest.cc",
diff --git a/api/video/test/i444_buffer_unittest.cc b/api/video/test/i444_buffer_unittest.cc
deleted file mode 100644
index 52ce49a..0000000
--- a/api/video/test/i444_buffer_unittest.cc
+++ /dev/null
@@ -1,112 +0,0 @@
-
-/*
- *  Copyright (c) 2021 The WebRTC project authors. All Rights Reserved.
- *
- *  Use of this source code is governed by a BSD-style license
- *  that can be found in the LICENSE file in the root of the source
- *  tree. An additional intellectual property rights grant can be found
- *  in the file PATENTS.  All contributing project authors may
- *  be found in the AUTHORS file in the root of the source tree.
- */
-
-#include "api/video/i444_buffer.h"
-
-#include "api/video/i420_buffer.h"
-#include "test/frame_utils.h"
-#include "test/gmock.h"
-#include "test/gtest.h"
-
-namespace webrtc {
-
-namespace {
-int GetY(rtc::scoped_refptr<I444BufferInterface> buf, int col, int row) {
-  return buf->DataY()[row * buf->StrideY() + col];
-}
-
-int GetU(rtc::scoped_refptr<I444BufferInterface> buf, int col, int row) {
-  return buf->DataU()[row * buf->StrideU() + col];
-}
-
-int GetV(rtc::scoped_refptr<I444BufferInterface> buf, int col, int row) {
-  return buf->DataV()[row * buf->StrideV() + col];
-}
-
-void FillI444Buffer(rtc::scoped_refptr<I444Buffer> buf) {
-  const uint8_t Y = 1;
-  const uint8_t U = 2;
-  const uint8_t V = 3;
-  for (int row = 0; row < buf->height(); ++row) {
-    for (int col = 0; col < buf->width(); ++col) {
-      buf->MutableDataY()[row * buf->StrideY() + col] = Y;
-      buf->MutableDataU()[row * buf->StrideU() + col] = U;
-      buf->MutableDataV()[row * buf->StrideV() + col] = V;
-    }
-  }
-}
-
-}  // namespace
-
-TEST(I444BufferTest, InitialData) {
-  constexpr int stride = 3;
-  constexpr int width = 3;
-  constexpr int height = 3;
-
-  rtc::scoped_refptr<I444Buffer> i444_buffer(I444Buffer::Create(width, height));
-  EXPECT_EQ(width, i444_buffer->width());
-  EXPECT_EQ(height, i444_buffer->height());
-  EXPECT_EQ(stride, i444_buffer->StrideY());
-  EXPECT_EQ(stride, i444_buffer->StrideU());
-  EXPECT_EQ(stride, i444_buffer->StrideV());
-  EXPECT_EQ(3, i444_buffer->ChromaWidth());
-  EXPECT_EQ(3, i444_buffer->ChromaHeight());
-}
-
-TEST(I444BufferTest, ReadPixels) {
-  constexpr int width = 3;
-  constexpr int height = 3;
-
-  rtc::scoped_refptr<I444Buffer> i444_buffer(I444Buffer::Create(width, height));
-  // Y = 1, U = 2, V = 3.
-  FillI444Buffer(i444_buffer);
-  for (int row = 0; row < height; row++) {
-    for (int col = 0; col < width; col++) {
-      EXPECT_EQ(1, GetY(i444_buffer, col, row));
-      EXPECT_EQ(2, GetU(i444_buffer, col, row));
-      EXPECT_EQ(3, GetV(i444_buffer, col, row));
-    }
-  }
-}
-
-TEST(I444BufferTest, ToI420) {
-  constexpr int width = 3;
-  constexpr int height = 3;
-  constexpr int size_y = width * height;
-  constexpr int size_u = (width + 1) / 2 * (height + 1) / 2;
-  constexpr int size_v = (width + 1) / 2 * (height + 1) / 2;
-  rtc::scoped_refptr<I420Buffer> reference(I420Buffer::Create(width, height));
-  memset(reference->MutableDataY(), 8, size_y);
-  memset(reference->MutableDataU(), 4, size_u);
-  memset(reference->MutableDataV(), 2, size_v);
-
-  rtc::scoped_refptr<I444Buffer> i444_buffer(I444Buffer::Create(width, height));
-  // Convert the reference buffer to I444.
-  memset(i444_buffer->MutableDataY(), 8, size_y);
-  memset(i444_buffer->MutableDataU(), 4, size_y);
-  memset(i444_buffer->MutableDataV(), 2, size_y);
-
-  // Confirm YUV values are as expected.
-  for (int row = 0; row < height; row++) {
-    for (int col = 0; col < width; col++) {
-      EXPECT_EQ(8, GetY(i444_buffer, col, row));
-      EXPECT_EQ(4, GetU(i444_buffer, col, row));
-      EXPECT_EQ(2, GetV(i444_buffer, col, row));
-    }
-  }
-
-  rtc::scoped_refptr<I420BufferInterface> i420_buffer(i444_buffer->ToI420());
-  EXPECT_EQ(height, i420_buffer->height());
-  EXPECT_EQ(width, i420_buffer->width());
-  EXPECT_TRUE(test::FrameBufsEqual(reference, i420_buffer));
-}
-
-}  // namespace webrtc
diff --git a/api/video/video_frame_buffer.cc b/api/video/video_frame_buffer.cc
index cf31e9d..7085010 100644
--- a/api/video/video_frame_buffer.cc
+++ b/api/video/video_frame_buffer.cc
@@ -11,7 +11,6 @@
 #include "api/video/video_frame_buffer.h"
 
 #include "api/video/i420_buffer.h"
-#include "api/video/i444_buffer.h"
 #include "api/video/nv12_buffer.h"
 #include "rtc_base/checks.h"
 
@@ -118,19 +117,6 @@
   return height();
 }
 
-rtc::scoped_refptr<VideoFrameBuffer> I444BufferInterface::CropAndScale(
-    int offset_x,
-    int offset_y,
-    int crop_width,
-    int crop_height,
-    int scaled_width,
-    int scaled_height) {
-  rtc::scoped_refptr<I444Buffer> result =
-      I444Buffer::Create(scaled_width, scaled_height);
-  result->CropAndScaleFrom(*this, offset_x, offset_y, crop_width, crop_height);
-  return result;
-}
-
 VideoFrameBuffer::Type I010BufferInterface::type() const {
   return Type::kI010;
 }
diff --git a/api/video/video_frame_buffer.h b/api/video/video_frame_buffer.h
index 6098a481..7b0782f 100644
--- a/api/video/video_frame_buffer.h
+++ b/api/video/video_frame_buffer.h
@@ -184,13 +184,6 @@
   int ChromaWidth() const final;
   int ChromaHeight() const final;
 
-  rtc::scoped_refptr<VideoFrameBuffer> CropAndScale(int offset_x,
-                                                    int offset_y,
-                                                    int crop_width,
-                                                    int crop_height,
-                                                    int scaled_width,
-                                                    int scaled_height) override;
-
  protected:
   ~I444BufferInterface() override {}
 };
diff --git a/api/video_codecs/h264_profile_level_id.cc b/api/video_codecs/h264_profile_level_id.cc
index 02b43ba..fa47758 100644
--- a/api/video_codecs/h264_profile_level_id.cc
+++ b/api/video_codecs/h264_profile_level_id.cc
@@ -68,8 +68,7 @@
     {0x58, BitPattern("10xx0000"), H264Profile::kProfileBaseline},
     {0x4D, BitPattern("0x0x0000"), H264Profile::kProfileMain},
     {0x64, BitPattern("00000000"), H264Profile::kProfileHigh},
-    {0x64, BitPattern("00001100"), H264Profile::kProfileConstrainedHigh},
-    {0xF4, BitPattern("00000000"), H264Profile::kProfilePredictiveHigh444}};
+    {0x64, BitPattern("00001100"), H264Profile::kProfileConstrainedHigh}};
 
 struct LevelConstraint {
   const int max_macroblocks_per_second;
@@ -229,9 +228,6 @@
     case H264Profile::kProfileHigh:
       profile_idc_iop_string = "6400";
       break;
-    case H264Profile::kProfilePredictiveHigh444:
-      profile_idc_iop_string = "f400";
-      break;
     // Unrecognized profile.
     default:
       return absl::nullopt;
diff --git a/api/video_codecs/h264_profile_level_id.h b/api/video_codecs/h264_profile_level_id.h
index 4b46ad3..51d025c 100644
--- a/api/video_codecs/h264_profile_level_id.h
+++ b/api/video_codecs/h264_profile_level_id.h
@@ -25,7 +25,6 @@
   kProfileMain,
   kProfileConstrainedHigh,
   kProfileHigh,
-  kProfilePredictiveHigh444,
 };
 
 // All values are equal to ten times the level number, except level 1b which is
diff --git a/common_video/include/video_frame_buffer_pool.h b/common_video/include/video_frame_buffer_pool.h
index f26a9f7..539a6cc 100644
--- a/common_video/include/video_frame_buffer_pool.h
+++ b/common_video/include/video_frame_buffer_pool.h
@@ -17,7 +17,6 @@
 
 #include "api/scoped_refptr.h"
 #include "api/video/i420_buffer.h"
-#include "api/video/i444_buffer.h"
 #include "api/video/nv12_buffer.h"
 #include "rtc_base/race_checker.h"
 #include "rtc_base/ref_counted_object.h"
@@ -44,7 +43,6 @@
   // and there are less than `max_number_of_buffers` pending, a buffer is
   // created. Returns null otherwise.
   rtc::scoped_refptr<I420Buffer> CreateI420Buffer(int width, int height);
-  rtc::scoped_refptr<I444Buffer> CreateI444Buffer(int width, int height);
   rtc::scoped_refptr<NV12Buffer> CreateNV12Buffer(int width, int height);
 
   // Changes the max amount of buffers in the pool to the new value.
diff --git a/common_video/video_frame_buffer_pool.cc b/common_video/video_frame_buffer_pool.cc
index cddb7c5..a450bd1 100644
--- a/common_video/video_frame_buffer_pool.cc
+++ b/common_video/video_frame_buffer_pool.cc
@@ -20,17 +20,12 @@
 bool HasOneRef(const rtc::scoped_refptr<VideoFrameBuffer>& buffer) {
   // Cast to rtc::RefCountedObject is safe because this function is only called
   // on locally created VideoFrameBuffers, which are either
-  // `rtc::RefCountedObject<I420Buffer>`, `rtc::RefCountedObject<I444Buffer>` or
-  // `rtc::RefCountedObject<NV12Buffer>`.
+  // `rtc::RefCountedObject<I420Buffer>` or `rtc::RefCountedObject<NV12Buffer>`.
   switch (buffer->type()) {
     case VideoFrameBuffer::Type::kI420: {
       return static_cast<rtc::RefCountedObject<I420Buffer>*>(buffer.get())
           ->HasOneRef();
     }
-    case VideoFrameBuffer::Type::kI444: {
-      return static_cast<rtc::RefCountedObject<I444Buffer>*>(buffer.get())
-          ->HasOneRef();
-    }
     case VideoFrameBuffer::Type::kNV12: {
       return static_cast<rtc::RefCountedObject<NV12Buffer>*>(buffer.get())
           ->HasOneRef();
@@ -121,37 +116,6 @@
   return buffer;
 }
 
-rtc::scoped_refptr<I444Buffer> VideoFrameBufferPool::CreateI444Buffer(
-    int width,
-    int height) {
-  RTC_DCHECK_RUNS_SERIALIZED(&race_checker_);
-
-  rtc::scoped_refptr<VideoFrameBuffer> existing_buffer =
-      GetExistingBuffer(width, height, VideoFrameBuffer::Type::kI444);
-  if (existing_buffer) {
-    // Cast is safe because the only way kI444 buffer is created is
-    // in the same function below, where |RefCountedObject<I444Buffer>|
-    // is created.
-    rtc::RefCountedObject<I444Buffer>* raw_buffer =
-        static_cast<rtc::RefCountedObject<I444Buffer>*>(existing_buffer.get());
-    // Creates a new scoped_refptr, which is also pointing to the same
-    // RefCountedObject as buffer, increasing ref count.
-    return rtc::scoped_refptr<I444Buffer>(raw_buffer);
-  }
-
-  if (buffers_.size() >= max_number_of_buffers_)
-    return nullptr;
-  // Allocate new buffer.
-  rtc::scoped_refptr<I444Buffer> buffer =
-      new rtc::RefCountedObject<I444Buffer>(width, height);
-
-  if (zero_initialize_)
-    buffer->InitializeData();
-
-  buffers_.push_back(buffer);
-  return buffer;
-}
-
 rtc::scoped_refptr<NV12Buffer> VideoFrameBufferPool::CreateNV12Buffer(
     int width,
     int height) {
diff --git a/modules/video_coding/codecs/h264/h264.cc b/modules/video_coding/codecs/h264/h264.cc
index eef4dde..275e634 100644
--- a/modules/video_coding/codecs/h264/h264.cc
+++ b/modules/video_coding/codecs/h264/h264.cc
@@ -87,10 +87,6 @@
           CreateH264Format(H264Profile::kProfileConstrainedBaseline,
                            H264Level::kLevel3_1, "1"),
           CreateH264Format(H264Profile::kProfileConstrainedBaseline,
-                           H264Level::kLevel3_1, "0"),
-          CreateH264Format(H264Profile::kProfilePredictiveHigh444,
-                           H264Level::kLevel3_1, "1"),
-          CreateH264Format(H264Profile::kProfilePredictiveHigh444,
                            H264Level::kLevel3_1, "0")};
 }
 
diff --git a/modules/video_coding/codecs/h264/h264_decoder_impl.cc b/modules/video_coding/codecs/h264/h264_decoder_impl.cc
index 31279b7..b42aac5 100644
--- a/modules/video_coding/codecs/h264/h264_decoder_impl.cc
+++ b/modules/video_coding/codecs/h264/h264_decoder_impl.cc
@@ -41,10 +41,8 @@
 
 namespace {
 
-constexpr std::array<AVPixelFormat, 2> kPixelFormatsDefault = {
-    AV_PIX_FMT_YUV420P, AV_PIX_FMT_YUV444P};
-constexpr std::array<AVPixelFormat, 2> kPixelFormatsFullRange = {
-    AV_PIX_FMT_YUVJ420P, AV_PIX_FMT_YUVJ444P};
+const AVPixelFormat kPixelFormatDefault = AV_PIX_FMT_YUV420P;
+const AVPixelFormat kPixelFormatFullRange = AV_PIX_FMT_YUVJ420P;
 const size_t kYPlaneIndex = 0;
 const size_t kUPlaneIndex = 1;
 const size_t kVPlaneIndex = 2;
@@ -78,17 +76,9 @@
   // Necessary capability to be allowed to provide our own buffers.
   RTC_DCHECK(context->codec->capabilities | AV_CODEC_CAP_DR1);
 
-  // Limited or full range YUV420 or YUV444 is expected.
-  auto pixelFormatDefault = std::find_if(
-      kPixelFormatsDefault.begin(), kPixelFormatsDefault.end(),
-      [context](AVPixelFormat format) { return context->pix_fmt == format; });
-  auto pixelFormatFullRange = std::find_if(
-      kPixelFormatsFullRange.begin(), kPixelFormatsFullRange.end(),
-      [context](AVPixelFormat format) { return context->pix_fmt == format; });
-
   // Limited or full range YUV420 is expected.
-  RTC_CHECK(pixelFormatDefault != kPixelFormatsDefault.end() ||
-            pixelFormatFullRange != kPixelFormatsFullRange.end());
+  RTC_CHECK(context->pix_fmt == kPixelFormatDefault ||
+            context->pix_fmt == kPixelFormatFullRange);
 
   // `av_frame->width` and `av_frame->height` are set by FFmpeg. These are the
   // actual image's dimensions and may be different from `context->width` and
@@ -122,43 +112,8 @@
   // http://crbug.com/390941. Our pool is set up to zero-initialize new buffers.
   // TODO(nisse): Delete that feature from the video pool, instead add
   // an explicit call to InitializeData here.
-  rtc::scoped_refptr<PlanarYuv8Buffer> frame_buffer;
-  rtc::scoped_refptr<I444Buffer> i444_buffer;
-  rtc::scoped_refptr<I420Buffer> i420_buffer;
-  switch (context->pix_fmt) {
-    case AV_PIX_FMT_YUV420P:
-    case AV_PIX_FMT_YUVJ420P:
-      i420_buffer =
-          decoder->ffmpeg_buffer_pool_.CreateI420Buffer(width, height);
-      // Set `av_frame` members as required by FFmpeg.
-      av_frame->data[kYPlaneIndex] = i420_buffer->MutableDataY();
-      av_frame->linesize[kYPlaneIndex] = i420_buffer->StrideY();
-      av_frame->data[kUPlaneIndex] = i420_buffer->MutableDataU();
-      av_frame->linesize[kUPlaneIndex] = i420_buffer->StrideU();
-      av_frame->data[kVPlaneIndex] = i420_buffer->MutableDataV();
-      av_frame->linesize[kVPlaneIndex] = i420_buffer->StrideV();
-      RTC_DCHECK_EQ(av_frame->extended_data, av_frame->data);
-      frame_buffer = i420_buffer;
-      break;
-    case AV_PIX_FMT_YUV444P:
-    case AV_PIX_FMT_YUVJ444P:
-      i444_buffer =
-          decoder->ffmpeg_buffer_pool_.CreateI444Buffer(width, height);
-      // Set `av_frame` members as required by FFmpeg.
-      av_frame->data[kYPlaneIndex] = i444_buffer->MutableDataY();
-      av_frame->linesize[kYPlaneIndex] = i444_buffer->StrideY();
-      av_frame->data[kUPlaneIndex] = i444_buffer->MutableDataU();
-      av_frame->linesize[kUPlaneIndex] = i444_buffer->StrideU();
-      av_frame->data[kVPlaneIndex] = i444_buffer->MutableDataV();
-      av_frame->linesize[kVPlaneIndex] = i444_buffer->StrideV();
-      frame_buffer = i444_buffer;
-      break;
-    default:
-      RTC_LOG(LS_ERROR) << "Unsupported buffer type " << context->pix_fmt
-                        << ". Check supported supported pixel formats!";
-      decoder->ReportError();
-      return -1;
-  }
+  rtc::scoped_refptr<I420Buffer> frame_buffer =
+      decoder->ffmpeg_buffer_pool_.CreateI420Buffer(width, height);
 
   int y_size = width * height;
   int uv_size = frame_buffer->ChromaWidth() * frame_buffer->ChromaHeight();
@@ -170,6 +125,15 @@
   av_frame->format = context->pix_fmt;
   av_frame->reordered_opaque = context->reordered_opaque;
 
+  // Set `av_frame` members as required by FFmpeg.
+  av_frame->data[kYPlaneIndex] = frame_buffer->MutableDataY();
+  av_frame->linesize[kYPlaneIndex] = frame_buffer->StrideY();
+  av_frame->data[kUPlaneIndex] = frame_buffer->MutableDataU();
+  av_frame->linesize[kUPlaneIndex] = frame_buffer->StrideU();
+  av_frame->data[kVPlaneIndex] = frame_buffer->MutableDataV();
+  av_frame->linesize[kVPlaneIndex] = frame_buffer->StrideV();
+  RTC_DCHECK_EQ(av_frame->extended_data, av_frame->data);
+
   // Create a VideoFrame object, to keep a reference to the buffer.
   // TODO(nisse): The VideoFrame's timestamp and rotation info is not used.
   // Refactor to do not use a VideoFrame object at all.
@@ -233,6 +197,7 @@
     av_context_->coded_width = resolution.Width();
     av_context_->coded_height = resolution.Height();
   }
+  av_context_->pix_fmt = kPixelFormatDefault;
   av_context_->extradata = nullptr;
   av_context_->extradata_size = 0;
 
@@ -352,103 +317,47 @@
   RTC_DCHECK(input_frame);
   rtc::scoped_refptr<VideoFrameBuffer> frame_buffer =
       input_frame->video_frame_buffer();
-
-  // Instantiate Planar YUV8 buffer according to video frame buffer type
-  const webrtc::PlanarYuv8Buffer* planar_yuv8_buffer = nullptr;
-  VideoFrameBuffer::Type video_frame_buffer_type = frame_buffer->type();
-  switch (video_frame_buffer_type) {
-    case VideoFrameBuffer::Type::kI420:
-      planar_yuv8_buffer = frame_buffer->GetI420();
-      break;
-    case VideoFrameBuffer::Type::kI444:
-      planar_yuv8_buffer = frame_buffer->GetI444();
-      break;
-    default:
-      // If this code is changed to allow other video frame buffer type,
-      // make sure that the code below which wraps I420/I444 buffer and
-      // code which converts to NV12 is changed
-      // to work with new video frame buffer type
-
-      RTC_LOG(LS_ERROR) << "frame_buffer type: "
-                        << static_cast<int32_t>(video_frame_buffer_type)
-                        << " is not supported!";
-      ReportError();
-      return WEBRTC_VIDEO_CODEC_ERROR;
-  }
+  const webrtc::I420BufferInterface* i420_buffer = frame_buffer->GetI420();
 
   // When needed, FFmpeg applies cropping by moving plane pointers and adjusting
   // frame width/height. Ensure that cropped buffers lie within the allocated
   // memory.
-  RTC_DCHECK_LE(av_frame_->width, planar_yuv8_buffer->width());
-  RTC_DCHECK_LE(av_frame_->height, planar_yuv8_buffer->height());
-  RTC_DCHECK_GE(av_frame_->data[kYPlaneIndex], planar_yuv8_buffer->DataY());
-  RTC_DCHECK_LE(av_frame_->data[kYPlaneIndex] +
-                    av_frame_->linesize[kYPlaneIndex] * av_frame_->height,
-                planar_yuv8_buffer->DataY() + planar_yuv8_buffer->StrideY() *
-                                                  planar_yuv8_buffer->height());
-  RTC_DCHECK_GE(av_frame_->data[kUPlaneIndex], planar_yuv8_buffer->DataU());
+  RTC_DCHECK_LE(av_frame_->width, i420_buffer->width());
+  RTC_DCHECK_LE(av_frame_->height, i420_buffer->height());
+  RTC_DCHECK_GE(av_frame_->data[kYPlaneIndex], i420_buffer->DataY());
+  RTC_DCHECK_LE(
+      av_frame_->data[kYPlaneIndex] +
+          av_frame_->linesize[kYPlaneIndex] * av_frame_->height,
+      i420_buffer->DataY() + i420_buffer->StrideY() * i420_buffer->height());
+  RTC_DCHECK_GE(av_frame_->data[kUPlaneIndex], i420_buffer->DataU());
   RTC_DCHECK_LE(av_frame_->data[kUPlaneIndex] +
                     av_frame_->linesize[kUPlaneIndex] * av_frame_->height / 2,
-                planar_yuv8_buffer->DataU() + planar_yuv8_buffer->StrideU() *
-                                                  planar_yuv8_buffer->height() /
-                                                  2);
-  RTC_DCHECK_GE(av_frame_->data[kVPlaneIndex], planar_yuv8_buffer->DataV());
+                i420_buffer->DataU() +
+                    i420_buffer->StrideU() * i420_buffer->height() / 2);
+  RTC_DCHECK_GE(av_frame_->data[kVPlaneIndex], i420_buffer->DataV());
   RTC_DCHECK_LE(av_frame_->data[kVPlaneIndex] +
                     av_frame_->linesize[kVPlaneIndex] * av_frame_->height / 2,
-                planar_yuv8_buffer->DataV() + planar_yuv8_buffer->StrideV() *
-                                                  planar_yuv8_buffer->height() /
-                                                  2);
+                i420_buffer->DataV() +
+                    i420_buffer->StrideV() * i420_buffer->height() / 2);
 
-  rtc::scoped_refptr<webrtc::VideoFrameBuffer> cropped_buffer;
-  if (video_frame_buffer_type == VideoFrameBuffer::Type::kI420) {
-    cropped_buffer = WrapI420Buffer(
-        av_frame_->width, av_frame_->height, av_frame_->data[kYPlaneIndex],
-        av_frame_->linesize[kYPlaneIndex], av_frame_->data[kUPlaneIndex],
-        av_frame_->linesize[kUPlaneIndex], av_frame_->data[kVPlaneIndex],
-        av_frame_->linesize[kVPlaneIndex],
-        // To keep reference alive.
-        [frame_buffer] {});
-  } else {
-    cropped_buffer = WrapI444Buffer(
-        av_frame_->width, av_frame_->height, av_frame_->data[kYPlaneIndex],
-        av_frame_->linesize[kYPlaneIndex], av_frame_->data[kUPlaneIndex],
-        av_frame_->linesize[kUPlaneIndex], av_frame_->data[kVPlaneIndex],
-        av_frame_->linesize[kVPlaneIndex],
-        // To keep reference alive.
-        [frame_buffer] {});
-  }
+  rtc::scoped_refptr<webrtc::VideoFrameBuffer> cropped_buffer = WrapI420Buffer(
+      av_frame_->width, av_frame_->height, av_frame_->data[kYPlaneIndex],
+      av_frame_->linesize[kYPlaneIndex], av_frame_->data[kUPlaneIndex],
+      av_frame_->linesize[kUPlaneIndex], av_frame_->data[kVPlaneIndex],
+      av_frame_->linesize[kVPlaneIndex],
+      // To keep reference alive.
+      [frame_buffer] {});
 
   if (preferred_output_format_ == VideoFrameBuffer::Type::kNV12) {
+    const I420BufferInterface* cropped_i420 = cropped_buffer->GetI420();
     auto nv12_buffer = output_buffer_pool_.CreateNV12Buffer(
-        cropped_buffer->width(), cropped_buffer->height());
-
-    const PlanarYuv8Buffer* cropped_planar_yuv8_buffer = nullptr;
-    if (video_frame_buffer_type == VideoFrameBuffer::Type::kI420) {
-      cropped_planar_yuv8_buffer = cropped_buffer->GetI420();
-      libyuv::I420ToNV12(cropped_planar_yuv8_buffer->DataY(),
-                         cropped_planar_yuv8_buffer->StrideY(),
-                         cropped_planar_yuv8_buffer->DataU(),
-                         cropped_planar_yuv8_buffer->StrideU(),
-                         cropped_planar_yuv8_buffer->DataV(),
-                         cropped_planar_yuv8_buffer->StrideV(),
-                         nv12_buffer->MutableDataY(), nv12_buffer->StrideY(),
-                         nv12_buffer->MutableDataUV(), nv12_buffer->StrideUV(),
-                         planar_yuv8_buffer->width(),
-                         planar_yuv8_buffer->height());
-    } else {
-      cropped_planar_yuv8_buffer = cropped_buffer->GetI444();
-      libyuv::I444ToNV12(cropped_planar_yuv8_buffer->DataY(),
-                         cropped_planar_yuv8_buffer->StrideY(),
-                         cropped_planar_yuv8_buffer->DataU(),
-                         cropped_planar_yuv8_buffer->StrideU(),
-                         cropped_planar_yuv8_buffer->DataV(),
-                         cropped_planar_yuv8_buffer->StrideV(),
-                         nv12_buffer->MutableDataY(), nv12_buffer->StrideY(),
-                         nv12_buffer->MutableDataUV(), nv12_buffer->StrideUV(),
-                         planar_yuv8_buffer->width(),
-                         planar_yuv8_buffer->height());
-    }
-
+        cropped_i420->width(), cropped_i420->height());
+    libyuv::I420ToNV12(cropped_i420->DataY(), cropped_i420->StrideY(),
+                       cropped_i420->DataU(), cropped_i420->StrideU(),
+                       cropped_i420->DataV(), cropped_i420->StrideV(),
+                       nv12_buffer->MutableDataY(), nv12_buffer->StrideY(),
+                       nv12_buffer->MutableDataUV(), nv12_buffer->StrideUV(),
+                       i420_buffer->width(), i420_buffer->height());
     cropped_buffer = nv12_buffer;
   }
 
diff --git a/sdk/objc/components/video_codec/RTCVideoEncoderH264.mm b/sdk/objc/components/video_codec/RTCVideoEncoderH264.mm
index 93ed03a..966eb3e 100644
--- a/sdk/objc/components/video_codec/RTCVideoEncoderH264.mm
+++ b/sdk/objc/components/video_codec/RTCVideoEncoderH264.mm
@@ -240,7 +240,6 @@
 
     case webrtc::H264Profile::kProfileConstrainedHigh:
     case webrtc::H264Profile::kProfileHigh:
-    case webrtc::H264Profile::kProfilePredictiveHigh444:
       switch (profile_level_id.level) {
         case webrtc::H264Level::kLevel3:
           return kVTProfileLevel_H264_High_3_0;